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Past Research on ASP.NET CAS (Code Access Security)
Dinis Cruz (amongst a few others) have been an strong defender of the need for Microsoft to focus on making CAS (Code Access Security) work.
The consolidation of this research can be seen in this presentation: Making the case for Sandbox v1.1 - Dinis Cruz - SD Conference.ppt
See this blog post for more details and links to related material.